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Updated: Sep 24, 2025

Study of Experimental Organ Donation Models for Lung Transplantation
Published on: March 15, 2024
Organ donation after self-inflicted injury: A single institution analysis
Courtney H Meyer1,2,3, April A Grant1,2, Nosayaba Enofe1,2
1Emory University School of Medicine, Atlanta, Georgia, USA.
Background:
This study sought to determine the contribution of self-inflicted injury-related deaths to local organ donation rates and analyze contributing factors.
Methods:
A retrospective review of adult patients with traumatic self-inflicted injuries was performed at a Level I trauma center from 2013 to 2017. Data were obtained from the institutional trauma registry and cross-referenced with the local organ procurement organization (OPO). Referral rates were analyzed and outcomes, demographics and injury characteristics were compared between patients who underwent donation versus those who did not.
Results:
142 adult patients presented with traumatic self-inflicted injury, and 100 (70.4%) had referral calls made to the local OPO. These patients were predominantly male (83%), and gunshot injuries accounted for 75% of all mechanisms. Sixty-four percent had organ referrals versus tissue referrals (34%), and 17 (26.6%) of those patients went on to donate. The median number of organs procured was 4 [IQR 0-5]. In multivariate analysis, for each year increase in age, patients were less likely to have an organ referral (OR = .96 [95% CI .93-.99]; p = .0134) and less likely to undergo donation (OR = .95 [95% CI .90-.99]; p = .0308).
Conclusions:
Self-inflicted injury, though tragic, may provide a significant contribution to the limited organ donor registry.
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