Related Experiment Video
Updated: Sep 24, 2025

05:46
Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024
535
Multifocal contact lens myopia control: central and peripheral retinal image quality
1Division of Neurobiology, University of California, Berkeley, Berkeley, CA, USA.
Clinical & Experimental Optometry
|May 9, 2022
Summary
Multifocal contact lenses may help control myopia by reducing near target blur, not by altering peripheral retinal image quality. This therapy is crucial for managing myopia progression in children.
Area of Science:
- Ophthalmology
- Optometry
- Vision Science
Background:
- Myopic defocus in the peripheral retina inhibits eye growth, motivating myopia control therapies like multifocal contact lenses.
- Understanding light-triggered eye-length regulation requires knowledge of retinal light spread, which is lacking for multifocal contact lenses.
Purpose of the Study:
- To estimate retinal image spread from multifocal contact lenses using computational modeling.
- To investigate the impact of multifocal zones on image quality in the central and peripheral retina.
Main Methods:
- Utilized "through-focus" diffraction computations in contact lens/eye models.
- Incorporated polychromatic light, chromatic aberrations, and an M-cone phototransduction layer.
- Analyzed point- and edge-spread distributions of phototransduction activation.
Main Results:
- Multifocal zones caused veiling for in-focus viewing and improved near-target image quality in the unaccommodated central retina.
- These image quality improvements were significantly reduced in the retinal periphery.
- The precise configuration of multifocal zones did not appear critical for therapeutic effects.
Conclusions:
- The therapeutic value of multifocal contact lenses for myopia control is likely due to reduced near-target blur, which lessens the stimulus for accommodation.
- The benefits are not strongly dependent on specific multifocal zone configurations or peripheral retinal image quality changes.
Related Concept Videos
Focusing of Light in the Eye
3.3K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.3K
Angle Closure Glaucoma: Treatment
772
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
772
Open Angle Glaucoma: Treatment
640
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
640
Glaucoma: Overview
838
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
838
Anatomy of the Eyeball
7.6K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.6K

