Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

2.9K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
2.9K
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

62.1K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
62.1K
Dosage Compensation02:50

Dosage Compensation

6.3K
In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will...
6.3K
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

8.8K
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
8.8K
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

1.9K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.9K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

838
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
838

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rethinking hypercortisolism screening in obesity and diabetes: A systematic review and meta-analysis.

Metabolism: clinical and experimental·2026
Same author

The use of pharmacotherapies in non-cirrhotic metabolic dysfunction-associated steatohepatitis: a UK expert consensus.

The lancet. Gastroenterology & hepatology·2026
Same author

Factors affecting the quality of life of adults living with congenital adrenal hyperplasia: a qualitative study of lived experience.

Endocrine connections·2026
Same author

Hepatic Events Prevention by Antihyperglycemic Therapies and Intervention Comparisons in Type 2 Diabetes: The HEPATIC-T2DM Network Meta-analysis.

Diabetes care·2026
Same author

Human MASLD is a diurnal disease driven by multisystem insulin resistance and reduced insulin availability at night.

Cell metabolism·2026
Same author

Immune Checkpoint Inhibitor Therapy Induced Hypophysitis; A Tertiary Care Centre Experience; Highlighting Detection, Treatment Outcomes and Long Term Endocrinopathies and Recovery.

Clinical endocrinology·2026
Same journal

Weight management in China: integrating mental health into routine obesity care.

The lancet. Diabetes & endocrinology·2026
Same journal

Innovation is key to transforming future obesity care.

The lancet. Diabetes & endocrinology·2026
Same journal

Out of touch medical care.

The lancet. Diabetes & endocrinology·2026
Same journal

ADA Scientific Sessions 2026: a line crossed.

The lancet. Diabetes & endocrinology·2026
Same journal

Endocrine-neuropsychological interplay underpinning maternal postpartum depression.

The lancet. Diabetes & endocrinology·2026
Same journal

Intermittent fasting to treat diabetes: time to update clinical practice guidelines.

The lancet. Diabetes & endocrinology·2026
See all related articles

Related Experiment Video

Updated: Sep 24, 2025

Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
04:20

Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model

Published on: July 12, 2024

1.9K

Is autonomous cortisol secretion sexually dimorphic?

Riccardo Pofi1, Jeremy W Tomlinson2

  • 1Oxford Centre for Diabetes, Endocrinology, and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7LE, UK; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

The Lancet. Diabetes & Endocrinology
|May 9, 2022
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice
09:37

Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice

Published on: August 13, 2020

11.4K
Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

3.2K

Related Experiment Videos

Last Updated: Sep 24, 2025

Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
04:20

Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model

Published on: July 12, 2024

1.9K
Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice
09:37

Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice

Published on: August 13, 2020

11.4K
Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

3.2K