Endothelial glycocalyx integrity in oncological patients

Kalliopi Keramida1, John Thymis2, Maria Anastasiou3

  • 12nd Department of Cardiology, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece; Cardiology Department, General Anti-Cancer, Oncological Hospital, Agios Savvas, Athens, Greece.

Summary

Cancer patients show impaired endothelial glycocalyx thickness, a marker of microvascular health, even before overt cardiotoxicity. This finding suggests perfused boundary region (PBR) measurements can help detect early cancer-related endothelial dysfunction.

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