Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Time-dependent facilitation of homologous actions.

Experimental brain research·2026
Same author

Visuo-spatial attention in younger and older adults: comparing performance on a series of computer-based tasks.

Acta psychologica·2026
Same author

Scalable, open-access and multidisciplinary data integration pipeline for climate-sensitive diseases.

Wellcome open research·2025
Same author

Transcranial direct current stimulation for upper and lower limb motor function in young people with Cerebral Palsy: a randomised controlled pilot study.

Disability and rehabilitation·2025
Same author

Early insights into eyeblink conditioning using optically pumped magnetometer-based MEG.

Frontiers in human neuroscience·2025
Same author

Lessons learnt from moving an intensive care unit into a new hospital.

Journal of the Intensive Care Society·2025

Related Experiment Video

Updated: Sep 24, 2025

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation
10:11

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation

Published on: January 3, 2020

11.3K

Timing is everything: Event-related transcranial direct current stimulation improves motor adaptation.

Matthew Weightman1, John-Stuart Brittain2, Alison Hall3

  • 1School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; Centre for Human Brain Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

Brain Stimulation
|May 9, 2022
PubMed
Summary

Cerebellar transcranial direct current stimulation (tDCS) paired with movement selectively enhances motor learning. This timing-dependent approach improves adaptation when stimulation coincides with action, unlike stimulation of the M1 area.

Keywords:
Motor adaptationPlasticityTDCS

More Related Videos

Transcranial Electrical Brain Stimulation in Alert Rodents
10:08

Transcranial Electrical Brain Stimulation in Alert Rodents

Published on: November 2, 2017

10.8K
Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function
07:47

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function

Published on: February 4, 2016

13.2K

Related Experiment Videos

Last Updated: Sep 24, 2025

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation
10:11

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation

Published on: January 3, 2020

11.3K
Transcranial Electrical Brain Stimulation in Alert Rodents
10:08

Transcranial Electrical Brain Stimulation in Alert Rodents

Published on: November 2, 2017

10.8K
Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function
07:47

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function

Published on: February 4, 2016

13.2K

Area of Science:

  • Neuroscience
  • Motor Control
  • Neuroplasticity

Background:

  • Motor learning theories emphasize event timing.
  • Transcranial direct current stimulation (tDCS) application lacks temporal precision.
  • A gap exists between motor learning principles and tDCS application.

Purpose of the Study:

  • Investigate the temporal specificity of tDCS.
  • Apply tDCS in short epochs synchronized with movement.
  • Examine tDCS effects during a motor adaptation task.

Main Methods:

  • Participants adapted to opposing force-fields with contextual cues.
  • Event-related tDCS (er-TDCS) applied over M1 or cerebellum during movement.
  • Stimulation delivered in brief (<3s) epochs during specific learning contexts.

Main Results:

  • Cerebellar er-tDCS yoked to movement selectively enhanced stimulated movements.
  • Interleaved, non-stimulated movements showed no enhancement.
  • M1 er-tDCS and sham stimulation did not improve motor adaptation.

Conclusions:

  • Coupling cerebellar stimulation with movement enhances timing-dependent plasticity.
  • Hebbian-like mechanisms may underlie improved learning with cerebellar tDCS.
  • Precise temporal application of tDCS is crucial for motor learning.