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Updated: Jun 3, 2026

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The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
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Stability of first and second premolars extraction space closure
Guilherme Janson1, Mayara Rizzo1, Marcelo Vinicius Valerio1
1Department of Orthodontics, Bauru Dental School, University of São Paulo, Bauru, São Paulo, Brazil.
Summary
The stability of orthodontic extraction space closure is similar whether first or second premolars are extracted. Relapse tendency is comparable between the two premolar extraction groups, indicating similar long-term outcomes.
Area of Science:
- Orthodontics
- Dental Arch Stability
- Tooth Movement
Background:
- Premolar extractions are common in orthodontics to resolve crowding and protrusion.
- Maintaining extraction space closure is crucial for long-term treatment success.
- Some studies indicate a tendency for relapse even with adequate occlusion post-treatment.
Purpose of the Study:
- To compare the long-term stability of extraction space closure between first and second premolar teeth.
- To evaluate the rate of extraction space reopening after orthodontic treatment.
Main Methods:
- Digitized dental casts from 72 patients were analyzed using a 3D scanner.
- Patients were divided into two groups: first premolar extractions (n=29) and second premolar extractions (n=43).
- Chi-square and t-tests compared space closure stability post-treatment and long-term.
Main Results:
- Overall, both first and second premolar extraction groups showed similar rates of extraction site reopening.
- The tendency for space reopening was comparable between the two groups.
- However, in patients with initially closed spaces, maxillary space reopening was greater after first premolar extractions.
Conclusions:
- The stability of orthodontic extraction space closure is similar for both first and second premolar extractions.
- Both extraction patterns demonstrate comparable long-term stability, with a slight caveat for maxillary first premolar sites.

