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Published on: February 6, 2021
Proceedings of the Second Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and
Shraddha Mainali1, Venkatesh Aiyagari2, Sheila Alexander3
1Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. shraddha.mainali@vcuhealth.org.
Abstract:
This proceedings article presents actionable research targets on the basis of the presentations and discussions at the 2nd Curing Coma National Institutes of Health (NIH) symposium held from May 3 to May 5, 2021. Here, we summarize the background, research priorities, panel discussions, and deliverables discussed during the symposium across six major domains related to disorders of consciousness. The six domains include (1) Biology of Coma, (2) Coma Database, (3) Neuroprognostication, (4) Care of Comatose Patients, (5) Early Clinical Trials, and (6) Long-term Recovery. Following the 1st Curing Coma NIH virtual symposium held on September 9 to September 10, 2020, six workgroups, each consisting of field experts in respective domains, were formed and tasked with identifying gaps and developing key priorities and deliverables to advance the mission of the Curing Coma Campaign. The highly interactive and inspiring presentations and panel discussions during the 3-day virtual NIH symposium identified several action items for the Curing Coma Campaign mission, which we summarize in this article.
Insights
The 2nd Curing Coma National Institutes of Health (NIH) symposium identified key research priorities for disorders of consciousness. Actionable targets were set across six domains to advance the Curing Coma Campaign mission.
Area of Science:
- Neuroscience
- Medical Research
Background:
- The Curing Coma Campaign aims to advance research for disorders of consciousness.
- The 2nd Curing Coma NIH symposium convened experts to discuss progress and future directions.
Purpose of the Study:
- To summarize actionable research targets identified at the 2nd Curing Coma NIH symposium.
- To outline priorities and deliverables across six key domains related to coma and disorders of consciousness.
Main Methods:
- Review of presentations and discussions from the 3-day virtual symposium (May 3-5, 2021).
- Synthesis of findings from six expert workgroups established after the 1st symposium.
Main Results:
- Identified research gaps and priorities in coma biology, databases, neuroprognostication, patient care, clinical trials, and long-term recovery.
- Defined key deliverables to advance the Curing Coma Campaign.
Conclusions:
- The symposium provided actionable research targets to accelerate progress in understanding and treating disorders of consciousness.
- The identified priorities will guide future research and clinical efforts in the Curing Coma Campaign.
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