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Novel conjugated small molecule-based nanoparticles for NIR-II photothermal antibacterial therapy
Wenying Jia1, Fangfang Huang2, Qiang Zhang1
1School of Materials Science & Engineering, Tianjin Key Laboratory for Photoelectric Materials and Devices, Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, Tianjin University of Technology, Tianjin 300384, China. luyan@tjut.edu.cn.
Abstract:
Single organic small molecule-based nanoparticles (CNPs) with strong responses within the NIR-II (1000-1350 nm) bio-window were prepared, and successfully applied as a highly efficient photothermal antibacterial agent for the first time. CNPs exhibit an outstanding bacteria inhibition efficiency of almost 100% against Staphylococcus aureus (S. aureus) with a high photothermal conversion efficiency (PTCE) of circa 49% under NIR-II laser irradiation (1064 nm) for 8 min.
