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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

66
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
66
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

81
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
81
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

89
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Kidney Structure01:45

Kidney Structure

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The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
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Related Experiment Video

Updated: Sep 24, 2025

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
11:47

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Published on: February 21, 2016

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Living kidney donation in a developing country.

Chandni Dayal1, Malcolm Davies1, Nina Elisabeth Diana1

  • 1Division of Nephrology, Department of Internal Medicine, University of the Witwatersrand, Johannesburg, South Africa.

Plos One
|May 10, 2022
PubMed
Summary

Living kidney donation faces challenges in Africa due to high comorbidity. However, careful donor selection ensures the procedure

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Area of Science:

  • Nephrology
  • Transplant Surgery
  • Public Health

Background:

  • Living kidney donation is crucial for addressing organ shortages.
  • High rates of comorbidity and familial kidney disease risk may limit donation in Africa.
  • Limited data exists on living kidney donation in African populations.

Purpose of the Study:

  • To evaluate reasons for non-donation among potential living kidney donors.
  • To assess post-donation outcomes in a South African cohort.
  • To identify factors influencing living donor nephrectomy in a developing world context.

Main Methods:

  • Retrospective analysis of 1208 potential living donors over 32 years.
  • Assessment of donor exclusion criteria and reasons for non-donation.
  • Follow-up evaluation of post-donation renal function and health outcomes.

Main Results:

  • Medical contraindications were the primary reason for donor exclusion.
  • Black donors faced higher exclusion rates, particularly for medical reasons.
  • Post-donation, 27% had reduced estimated glomerular filtration rate, 4% developed albuminuria, and 12.8% developed hypertension; no donor required kidney replacement therapy.
  • Black ethnicity did not correlate with increased adverse post-donation outcomes.

Conclusions:

  • Significant medical comorbidity presents challenges for living kidney donation in this population.
  • The study provides reassurance regarding the safety of living kidney donation in carefully selected individuals in developing countries.