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Updated: Sep 24, 2025

Compost Microcosms as Microbially Diverse, Natural-like Environments for Microbiome Research in Caenorhabditis elegans
Published on: September 13, 2022
Microbiomes: How a gut bacterium promotes healthier living in a nematode
1Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote Institute for Infectious Disease Research, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON L8S 4L8, Canada.
Abstract:
A new study finds that a bacterium from the microbiome of the nematode Pristionchus pacificus can promote rapid growth, increased body size, and increased fecundity by inducing neuronal expression of TGF-β ligands. This is an intriguing example of how the microbiota induces systemic effects in the host by stimulating neuroendocrine signaling.
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