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Updated: Sep 24, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis
Saad Al Bakr1, Mufaddal A Alaithan1
1From the Internal Medicine and Rheumatology, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia.
Abstract:
COVID vaccinations have been an important step in controlling the COVID-19 pandemic. Despite the fact they were generally safe and effective, a few case reports of renal disorders have been published following COVID vaccines. We report a 29-year-old man with history of Chronic Kidney Disease who presented to our center with flank pain after receiving AstraZeneca COVID vaccine. He also had history of raw milk ingestion. His initial investigations showed high creatinine with high level of proteinuria. A renal biopsy was consistent with immune complex-mediated glomerulonephritis on top of renal fibrosis. His brucella serology also showed high titer. He was started on treatment for Brucellosis and planned for follow-up afterwards for further therapy. To the best of our knowledge, this is the first reported case of concomitant Brucellosis and post COVID vaccine glomerulonephritis.
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