Related Experiment Video
Updated: Sep 24, 2025
09:50
A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
Published on: November 2, 2019
8.3K
Chronic lymphoedema: a nidus for squamous cell carcinoma
Shrea Gulati1, Sheragaru Hanumanthappa Chandrashekhara2, Sandeep Bhoriwal3
1Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, Delhi, India.
BMJ Case Reports
|May 10, 2022
Summary
Lymphoedema, a condition of lymphatic obstruction causing swelling, can lead to cancer. This case highlights squamous cell carcinoma developing in a patient with chronic lymphoedema.
Area of Science:
- Oncology
- Lymphatic Diseases
Background:
- Lymphoedema is a chronic condition resulting from lymphatic obstruction, leading to persistent swelling.
- Secondary lymphoedema is more prevalent than primary lymphoedema.
- Filariasis is a significant etiological factor for lymphoedema in endemic regions.
Observation:
- Chronic lymphoedema is associated with an increased risk of developing neoplasms.
- Common complications include cellulitis, lymphangiosarcoma, and various carcinomas.
- This report details a rare instance of squamous cell carcinoma arising in a patient with pre-existing chronic lymphoedema.
Findings:
- The study focuses on a case report of a woman in her 60s.
- The patient developed squamous cell carcinoma.
- The carcinoma occurred in the context of chronic lymphoedema.
Implications:
- This case underscores the importance of monitoring patients with chronic lymphoedema for neoplastic changes.
- Early detection and management of lymphoedema-associated cancers are crucial.
- Further research into the link between lymphoedema and cancer development is warranted.
More Related Videos
Related Concept Videos
01:30Skin Cancer
4.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.7K
01:15Secondary Lymphoid Organs
4.2K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
4.2K
01:18Lymphoid Cells and Tissues
1.6K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
1.6K
01:15Development of the Lymphatic System
1.1K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
1.1K