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The International Guideline Evaluation Screening Tool (IGEST): development and validation.

Daniela D'angelo1, Daniela Coclite1, Antonello Napoletano1

  • 1National Center for Clinical Excellence, Healthcare Quality and Safety, Istituto Superiore di Sanità, Via Giano della Bella, 34, 00162, Rome, Italy.

BMC Medical Research Methodology
|May 10, 2022
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Summary

A new tool, the International Guideline Evaluation Screening Tool (IGEST), effectively screens clinical practice guidelines for trustworthiness. This aids in efficient guideline adaptation by ensuring quality and supporting decision-making.

Keywords:
AssessmentClinical guidelineDevelopmentToolValidity

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Area of Science:

  • Health Services Research
  • Clinical Practice Guidelines
  • Evidence-Based Medicine

Background:

  • Guideline adaptation offers an efficient alternative to de novo development, reducing duplication.
  • Evaluating international guidelines is crucial for successful adaptation.
  • A new tool, the International Guideline Evaluation Screening Tool (IGEST), was developed to screen clinical practice guidelines (CPGs).

Purpose of the Study:

  • To describe the development and validation of the IGEST.
  • To create a tool for screening trustworthy CPGs for adoption/adaptation.
  • To facilitate the selection of high-quality international guidelines.

Main Methods:

  • The IGEST development involved two phases: tool development and content validation.
  • Tool development included defining scope, generating, and refining the item pool.
  • Content validation used a content validity index (CVI) based on expert panel opinions.

Main Results:

  • All IGEST items achieved a CVI >0.78, validating the instrument.
  • The final IGEST includes four preliminary conditions and 12 criteria across three dimensions.
  • Dimensions cover conflict of interest management, evidence quality/coherence, and panel composition.

Conclusions:

  • The IGEST demonstrates good content validity for assessing international guideline quality.
  • Using the IGEST can increase the adoption/adaptation of trustworthy international guidelines.
  • The tool provides a quick screening method and an acceptability threshold to support decision-making.