Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

63
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
63
Heart Valves01:16

Heart Valves

6.0K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
6.0K
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

54
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
54
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

56
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
56
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

67
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
67
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

54
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
54

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Isolated aortic valve-sparing aortic root replacement in elective patients with bicuspid aortic valve: A single-center experience.

JTCVS open·2026
Same author

Comparison of the Self-Expandable Intra-Annular Navitor Prosthesis with the Balloon-Expandable, Intra-Annular Sapien 3 Prosthesis: A Propensity-Matched Analysis.

Journal of clinical medicine·2026
Same author

Robot-Assisted Coronary Artery Bypass Versus Percutaneous Coronary Intervention in Patients With Coronary Artery Disease: A Meta-Analysis.

Innovations (Philadelphia, Pa.)·2026
Same author

Long-term results of mitral valve repair using leaflet resection versus chordae replacement.

JTCVS techniques·2026
Same author

Initial Experience of Non-Atriotomy Surgical Ablation During Coronary Artery Bypass Grafting With Preexisting Atrial Fibrillation: A Multicenter Study.

Annals of thoracic surgery short reports·2026
Same author

Robotically-assisted, totally endoscopic myocardial bridge unroofing: surgical technique.

Journal of visualized surgery·2026

Related Experiment Video

Updated: Sep 23, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.2K

Aortic valve neocuspidization: Frequently asked technical questions.

Andrea Amabile1, Gianluca Torregrossa2, Ellelan Degife1

  • 1Department of Surgery, Division of Cardiac Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.

Journal of Cardiac Surgery
|May 10, 2022
PubMed
Summary

Aortic valve neocuspidization, a technique described in 2011, has seen over 5500 procedures globally. This report details the essential nuances for mastering this reproducible method for aortic valve disease treatment.

Keywords:
valve repair/replacement

More Related Videos

Isolation of Human Primary Valve Cells for In vitro Disease Modeling
07:31

Isolation of Human Primary Valve Cells for In vitro Disease Modeling

Published on: April 16, 2021

2.9K
Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
05:47

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro

Published on: May 10, 2021

4.2K

Related Experiment Videos

Last Updated: Sep 23, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.2K
Isolation of Human Primary Valve Cells for In vitro Disease Modeling
07:31

Isolation of Human Primary Valve Cells for In vitro Disease Modeling

Published on: April 16, 2021

2.9K
Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
05:47

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro

Published on: May 10, 2021

4.2K

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Biomaterials

Background:

  • Aortic valve neocuspidization has emerged as a significant advancement in treating aortic valve disease since its inception in 2011.
  • Over 5500 procedures have been performed worldwide, demonstrating growing clinical adoption and interest.
  • Short- and mid-term outcomes reported thus far are promising, indicating the potential efficacy of this technique.

Purpose of the Study:

  • To elucidate the critical nuances required for mastering aortic valve neocuspidization.
  • To provide a standardized approach for surgeons seeking to implement this technique.
  • To contribute to the growing body of knowledge on aortic valve repair strategies.

Main Methods:

  • Detailed description of the standardized aortic valve neocuspidization technique.
  • Emphasis on key procedural steps and potential challenges.
  • Review of critical factors contributing to reproducibility.

Main Results:

  • The technique is highly reproducible when specific nuances are applied.
  • Successful implementation leads to favorable short- and mid-term outcomes.
  • Mastery of the technique is achievable through focused training and adherence to standardization.

Conclusions:

  • Aortic valve neocuspidization is a viable and reproducible option for aortic valve disease.
  • Understanding and applying the technique's nuances are crucial for successful patient outcomes.
  • Further research and training are essential to broaden the application of this innovative procedure.