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DNA-induced synthesis of biomimetic enzyme for sensitive detection of superoxide anions released from live cell

Ailing Ding1, Bin Wang1, Xiaoqing Ma1

  • 1Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University Chongqing 400715 P. R. China bwang@swu.edu.cn ecmli@swu.edu.cn.

RSC Advances
|May 11, 2022
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...