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Published on: June 9, 2023
Label-free identification carbapenem-resistant Escherichia coli based on surface-enhanced resonance Raman scattering
Jia Li1, Chongwen Wang2,3, Haiquan Kang1,3
1Medical Technology Institute of Xuzhou Medical University Xuzhou 221004 PR China sqwang@bmi.ac.cn.
Abstract:
In this study, a surface-enhanced resonance Raman scattering (SERRS) method has been developed for the accurate detection and identification of carbapenem-resistant and carbapenem-sensitive Escherichia coli. A total of 89 human isolates of Enterobacteriaceae, comprising 41 strains of carbapenem-sensitive E. coli (CSEC) and 48 strains of carbapenem-resistant E. coli (CREC), were tested to assess the feasibility of our proposed SERRS method as a clinical tool, and the results showed almost 100% accuracy.
