Related Experiment Video
Updated: Sep 23, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
Xiaoxia Liang1, Yingying Gao1, Shangxian Luan1
1Natural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University Chengdu 611130 P. R. China liangxiaoxial@sicau.edu.cn +86-028-8629-1162.
Abstract:
The important pharmacological activities and structural complexity of diterpenoid alkaloids have long stimulated strong scientific interest; some of these naturally abundant compounds have been reported to be highly promising for treating cancer. From 2008 to 2018, the cytotoxicity activities of more than 250 diterpenoid alkaloids were tested against several cancer cell lines. This review focuses on the progress of diterpenoid alkaloids with different structures derived from Ranunculaceae plants and some of their derivatives with potential anticancer activities. Then, we discuss the application prospects and development of active diterpenoid alkaloids.
Related Concept Videos
Drugs that Destabilize Microtubules
Inhibition of Cdk Activity
Targeted Cancer Therapies
There are several types of targeted therapies against...

