Related Experiment Video
Updated: Jun 27, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Hyoscine butylbromide induced psychosis: A case report
Nimesh Lageju1, Durga Neupane1, Lokesh Shekher Jaiswal2
1MBBS B.P. Koirala Institute of Health Sciences Dharan Nepal.
Insights
Hyoscine butylbromide can rarely cause psychosis in children. This rare side effect may present as acute cognitive decline and psychotic symptoms, even with typical use for abdominal pain.
Area of Science:
- Pediatric Neurology
- Clinical Toxicology
Background:
- Hyoscine butylbromide is a common anticholinergic medication used for abdominal pain.
- Psychosis is a rare but serious adverse effect associated with anticholinergic drugs.
Observation:
- A 9-year-old child presented with acute deterioration of cognitive functions.
- The child exhibited psychotic features, including altered perception and thought processes.
- The patient was concurrently taking hyoscine butylbromide for non-specific abdominal pain.
Findings:
- The clinical presentation suggested a diagnosis of hyoscine butylbromide-induced psychosis.
- This case highlights the potential for acute neuropsychiatric adverse events with this medication in pediatric patients.
Implications:
- Clinicians should consider hyoscine butylbromide-induced psychosis in the differential diagnosis of acute cognitive and psychotic disturbances in children.
- Awareness of this rare adverse effect is crucial for timely diagnosis and management.
- Further research may be warranted to understand the mechanisms and risk factors for this rare reaction.
Abstract:
Hyoscine butylbromide-induced pyschosis, though rare, should be considered in a child presenting with deteriorating cognitive functions and psychotic features acutely as evident in our case of a 9-year-old child taking hyoscine for her non-specific abdominal pain.
More Related Videos
07:02A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
Published on: February 11, 2019
04:06Author Spotlight: Challenges in Developing Dry Eye Animal Models and Future Research Directions
Published on: February 9, 2024
Related Concept Videos
Halogenation of Alkenes
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
Psychosis and Antipsychotic Drugs: Overview
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Psychosis: Goals of Pharmacotherapy
Mania and Antimanic Drugs: Overview
Positive Symptoms Schizophrenia: Hallucinations and Delusions
Hallucinations
Hallucinations in...