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Updated: Sep 23, 2025
3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
Published on: April 24, 2019
The facile synthesis and bioactivity of a 3D nanofibrous bioglass scaffold using an amino-modified bacterial
Cuilian Wen1, Yun Hong1, Junru Wu1
1College of Materials Science and Engineering, Fuzhou University, Key Laboratory of Eco-materials Advanced Technology (Fuzhou University), Fujian Province University Fuzhou 350116 China clwen@fzu.edu.cn.
Abstract:
Porous bioglass (BG) scaffolds are of great importance in tissue engineering because of their excellent osteogenic properties for bone regeneration. Herein, we reported for the first time the use of amino-modified bacterial cellulose (NBC) as a template to prepare a three-dimensional (3D) nanofibrous BG scaffold by a facile modified sol-gel approach under ultrasonic treatment. The results suggested that the amino groups on the BC template could effectively promote the absorption of the deposited CaO and SiO2 precursors, and the as-obtained BG scaffold showed a 3D interconnected porous network structure consisting of nanofibers with a diameter of about 20 nm. Furthermore, the as-obtained BG scaffold showed very good bioactivity after being immersed in SBF for 7 days. This research provides a facile and efficient way to prepare a nanofibrous BG scaffold with 3D porous structure, which can be used as a promising candidate for biomedical applications.
