Orbital histiocytic lymphoma arising from the ethmoid sinus

Histiocytic lymphoma has been reported previously as an orbital manifestation of systemic malignancy. We report herein a 49-year-old white male with orbital involvement from a sclerosing lesion in the ethmoid sinus that initially caused a biopsy-proven orbital inflammatory mass. This report of an orbito-sinus histiocytic lymphoma underscores the need to re-biopsy symptomatic orbital inflammatory lesions that continue to enlarge.