Metabolomics biotechnology, applications, and future trends: a systematic review

Area of Science:

• Biochemistry
• Biotechnology
• Medical Science

Background:

• Human disease incidence is increasing, necessitating a deeper understanding of endogenous metabolism.
• Metabolomics, particularly mass spectrometry-based approaches, is crucial for disease research.
• Investigating metabolites is challenging and time-consuming.

Purpose of the Study:

• To review metabolomics biotechnology.
• To highlight the application of metabolomics in elucidating disease mechanisms.
• To emphasize the role of mass spectrometry in metabolite discovery and identification.

Main Methods:

• Mass spectrometry (MS) is a highly sensitive and specific technology.
• MS is widely applied in life sciences for identifying endogenous substances.
• Metabolomics combined with MS facilitates biomarker discovery.

Main Results:

• Mass spectrometry provides essential technical support for life science research.
• The integration of metabolomics and MS is significant for identifying metabolite biomarkers.
• This approach enhances the exploration of metabolic disturbances in diseases.

Conclusions:

• Metabolomics, powered by mass spectrometry, is a vital tool for understanding disease.
• It accelerates the discovery and identification of metabolite biomarkers.
• Further development of MS technology will advance life science research and disease mechanism elucidation.