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Published on: June 15, 2018
The role of miRNA-210 in pre-eclampsia development
Ilona Jaszczuk1, Dorota Koczkodaj1, Adrianna Kondracka2
1Department of Cancer Genetics with Cytogenetic Laboratory, Medical University of Lublin, Lublin, Poland.
Abstract:
MicroRNAs (miRNAs) are a class of small non-coding, single-stranded RNAs (ribonucleic acids) that play important roles in many vital processes through their impact on gene expression. One such miRNA, miR210, represents a hypoxia-induced cellular miRNA group that hold a variety of functions. This review article highlights the importance of miR-210 in the development of pre-eclampsia.KEY MESSAGEmiR-210 is a promising biomarker for monitoring pregnancy with pre-eclampsia. Overexpression of miR-210 had a negative impact on the process of cell migration and trophoblast invasion.

