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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Characteristics of suicidal attacks in pregnancy; a multicenter study
Seda Akgün Kavurmaci1, İsmet Hortu2, Orkun Ilgen3
1Department of Obstetrics and Gynecology, Ataturk Training and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey.
Pregnant women attempting suicide, particularly in the first trimester, face significant risks. Early psychiatric screening during pregnancy is crucial for early detection and intervention, improving maternal-fetal health outcomes.
Area of Science:
- Obstetrics and Gynecology
- Public Health
- Psychiatry
Background:
- Suicide attempts (SA) during pregnancy pose a significant public health concern, encompassing maternal and fetal mortality risks.
- Understanding regional variations in SA methods, gestational week distribution, and common drug choices is vital for targeted prevention.
- Pregnancy-associated SA necessitates specialized attention due to combined maternal-fetal health implications.
Purpose of the Study:
- To investigate the characteristics and outcomes of suicide attempts in pregnant women admitted to emergency departments.
- To identify risk factors and common methods associated with SA in pregnancy.
- To inform preventive strategies and improve maternal-fetal health outcomes.
Main Methods:
- Retrospective analysis of pregnant women admitted for SA to three university hospital emergency departments (2015-2020).
- Data collection included SA features, demographic variables (age, gravidity, gestational week), and pregnancy outcomes.
- Analysis of obstetric and non-obstetric injuries.
Main Results:
- A total of 78 pregnant women were analyzed, with a mean age of 26.9 years.
- SA occurred most frequently in the first trimester (42.3%) and least in the third trimester (20.5%).
- High-dose drug intake (89.7%) was the predominant method, with paracetamol, iron/folic acid, and antidepressants being common choices.
Conclusions:
- Pregnant women are vulnerable to SA, especially in the first trimester, with 75% lacking prior psychiatric diagnoses.
- Routine psychiatric evaluation during pregnancy, particularly in the first trimester, is recommended for early detection of risk factors.
- Awareness of high-dose treatment protocols for common drugs like paracetamol is crucial for emergency physicians and obstetricians to improve maternal-fetal outcomes.
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