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Updated: Sep 23, 2025

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
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First-degree atrioventricular block in 14-year-old child due to Lyme disease

Halyna Lytvyn1, Natella Basa2, Khrystyna Slivinska-Kurchak3

  • 1Department of Pediatric Infectious Diseases, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.

Journal of Infection in Developing Countries
|May 11, 2022
PubMed

Insights

Lyme borreliosis can cause heart issues like atrioventricular block. Prompt antibiotic treatment with doxycycline resolved the condition in a young patient, highlighting early intervention for Lyme disease cardiovascular symptoms.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Bacteriology

Background:

  • Lyme disease is a tick-borne illness caused by Borrelia burgdorferi sensu lato (Bbsl) bacteria.
  • It commonly affects the skin, heart, nervous system, and joints.

Observation:

  • A 14-year-old boy presented with first-degree atrioventricular block, a cardiovascular manifestation of Lyme borreliosis.
  • Neither the patient nor his parents recalled a tick bite or erythema migrans (EM).

Findings:

  • The case highlights cardiovascular involvement as an initial presentation of Lyme disease.
  • Treatment with doxycycline led to the resolution of the atrioventricular block.

Implications:

  • Early diagnosis and treatment of Lyme borreliosis are crucial, even without typical early signs like EM.
  • Cardiovascular symptoms should be considered in the differential diagnosis of Lyme disease.
Keywords:
ECGLyme carditisLyme diseaseatrioventricular blockticks

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