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A case of mycotic keratitis due to Fusarium sp. with an undesirable outcome

Marija Trenkić1, Gordana Stanković Babić1, Marina Randelović2

  • 1Department of Ophthalmology, Faculty of Medicine, University of Niš, Serbia.

Journal of Infection in Developing Countries
|May 11, 2022
PubMed

Insights

Fungal keratitis, a serious eye infection, can cause irreversible damage if untreated. Prompt diagnosis and antifungal treatment are crucial for managing Fusarium spp. infections and preventing severe outcomes like evisceration.

Area of Science:

  • Ophthalmology
  • Mycology

Background:

  • Fungal keratitis is a significant cause of vision loss, particularly in developing regions.
  • Early diagnosis and intervention are critical to prevent irreversible corneal damage.

Observation:

  • A 60-year-old male presented with acute onset of fungal keratitis (Fusarium spp.) in the right eye.
  • Clinical signs included decreased visual acuity, photophobia, redness, pain, a corneal ulcer, and hypopyon.

Findings:

  • Initial antifungal therapy was administered based on preliminary microbiological results.
  • Treatment non-adherence led to disease progression, resulting in a full-thickness corneal infiltrate and severe anterior chamber reaction.
  • The patient ultimately required evisceration due to the advanced infection.

Implications:

  • This case highlights the importance of timely and complete antifungal treatment for fungal keratitis.
  • The need for established treatment protocols and accessible antifungal medications in regions with high prevalence is emphasized.
Keywords:
Fusarium spp.antifungaleviscerationkeratitistreatment

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