Related Experiment Video
Updated: Sep 23, 2025
09:02
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
4.6K
Intrarenal pressures during percutaneous nephrolithotomy: a porcine kidney model
Lee Chien Yap1, Donnacha Hogan1, Kenneth Patterson1
1Department of Urology, Mercy University Hospital, Cork, Ireland.
Scandinavian Journal of Urology
|May 12, 2022
Summary
Lower irrigation height and ureteric catheter use reduce intrarenal pressure (IRP) during percutaneous nephrolithotomy (PCNL). Mini-PCNL increases IRP, necessitating careful management to avoid adverse outcomes.
Area of Science:
- Urology
- Surgical Technology
- Medical Devices
Background:
- Elevated intrarenal pressure (IRP) during endoscopic lithotripsy correlates with adverse outcomes.
- Percutaneous intrarenal surgery (PCNL) involves managing IRP.
- Ex vivo porcine models are utilized to study surgical parameters.
Purpose of the Study:
- To evaluate the impact of different devices on IRP during PCNL.
- To compare IRP variations across different surgical techniques and device configurations.
- To identify methods for mitigating elevated IRP in PCNL.
Main Methods:
- Porcine urinary tracts were used to simulate PCNL.
- Intrarenal pressure was measured using cystometry software.
- Variations included access sheath size, irrigation height (100cm vs 60cm), ureteric catheter use, and suction.
Main Results:
- Lower irrigation height (60cm) significantly reduced IRP compared to 100cm.
- Mini-PCNL resulted in significantly higher IRP than conventional PCNL.
- Ureteric catheter use significantly decreased IRP at both irrigation heights.
Conclusions:
- Standard PCNL tract sizes show significant IRP variations based on irrigation fluid height.
- Mini-PCNL poses a higher risk of pathological IRP.
- Ureteric catheter use is a key factor in reducing IRP during PCNL.
