Related Experiment Video

Updated: Sep 23, 2025

Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles
10:16

Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles

Published on: August 17, 2022

3.4K

COVID-19 Vaccine Challenges in Developing and Developed Countries

Harshani Yarlagadda1, Meet A Patel2, Vasu Gupta3

  • 1Internal Medicine, Avalon University School of Medicine, Willemstad, CUW.

Cureus
|May 13, 2022
PubMed

Insights

The COVID-19 pandemic caused distress, leading to vaccine development. Challenges remain in vaccine accessibility, affordability, and acceptance globally, differing between developed and developing nations.

Area of Science:

  • Public Health
  • Epidemiology
  • Vaccinology

Background:

  • The COVID-19 pandemic resulted in widespread psychological and economic hardship.
  • Rapid development of COVID-19 vaccines occurred within a year of the pandemic declaration.

Purpose of the Study:

  • To examine the multifaceted challenges in achieving global herd immunity against COVID-19.
  • To identify disparities in vaccine-related challenges between developed and developing countries.

Main Methods:

  • Review of pandemic response strategies.
  • Analysis of global vaccine distribution and uptake data.
  • Comparative assessment of vaccine challenges across different economic contexts.

Main Results:

  • Key challenges include vaccine development, affordability, accessibility, and individual/country-level acceptance.
  • Developed nations primarily face vaccine acceptance issues.
  • Developing nations grapple with vaccine affordability and accessibility.

Conclusions:

  • Global herd immunity for COVID-19 is hindered by distinct challenges in different countries.
  • Addressing vaccine acceptance in developed nations and affordability/accessibility in developing nations is crucial for pandemic control.

Keywords:
covid-19herd immunitypandemicvaccinevaccine acceptabilityvaccine affordability

More Related Videos

Synthesis and Characterization of mRNA-Loaded PolyBeta Aminoesters Nanoparticles for Vaccination Purposes08:27

Synthesis and Characterization of mRNA-Loaded PolyBeta Aminoesters Nanoparticles for Vaccination Purposes

Published on: August 13, 2021

4.7K
Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

1.3K

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
45.4K
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
467
Methods Of Healthcare Delivery System01:26

Methods Of Healthcare Delivery System

At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.5K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.9K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
405
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.2K