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Updated: Sep 23, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Recyclable Cu/C3N4 composite catalyzed AHA/A3 coupling reactions for the synthesis of propargylamines
Hang Xu1, Jun Wang1, Peng Wang1
1Department of Applied Chemistry, School of Material Science and Technology, Nanjing University of Aeronautics and Astronautics Nanjing 210016 PR China yaoxq@nuaa.edu.cn.
Abstract:
The heterogeneous Cu/C3N4 catalyst was found to be efficient for the synthesis of propargylamines using a three-component coupling reaction of alkynes, CH2Cl2 and amines (AHA) without additional base. Moreover, the catalyst also showed highly catalytic activity in the synthesis of C1-alkynylated tetrahydroisoquinolines (THIQs) via an A3 reaction of alkynes, aldehydes and THIQ. The Cu/C3N4-catalyzed multicomponent reactions exhibited good functional group tolerance in most examples. Furthermore, the easily prepared Cu/C3N4 catalyst could be recovered and reused conveniently over 5 times without losing catalytic activities.
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