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Published on: February 17, 2021
Novel nanotechnological approaches for treatment of skin-aging
Ashmita Sharma1, Anurag Kuhad1, Ranjana Bhandari1
1University Institute of Pharmaceutical Sciences, UGC-Centre of Advanced Study, Panjab University, Chandigarh, 160 014, India.
Abstract:
One of the essential organs and protective barricades, the skin, needs to be taken care of early. Skin is affected by several intrinsic and extrinsic factors, and despite their morphological and pathological differences, they have many molecular similarities. As of today, various mechanisms and theories have been recommended for aging, such as cellular anility, reduced proliferative tendency, reduction in length of telomere, mutations in DNA, theory of free radical generation, and many others. In today's society, skin health is often considered an important indicator of health, which has led to an increased demand for anti-aging products. However, numerous conventional cosmetics and phytocompounds (curcumin, Vitamin E, resveratrol) utilized in anti-aging products have inimical physical and chemical attributes, including insufficient chemical stability and inadequate skin penetration bound their effectuality after topical administration. So recently, new novel nanotechnological approaches for preventing skin aging, such as liposomes, niosomes, solid lipid nanoparticles, transferosomes, ethosomes, nanostructured lipid carriers, and carbon nanotubes, are being used. Hence, the field of cosmeceutical nanomaterials is rapidly evolving, and we can look forward to seeing a variety of innovative nanotechnology-based cosmetic products be a game-changer for this multi-million anti-aging cosmetic industry.
Insights
Skin aging is influenced by intrinsic and extrinsic factors. Novel nanotechnology-based cosmeceuticals offer improved delivery and stability over conventional anti-aging products, revolutionizing the industry.
Area of Science:
- Cosmeceutical Science
- Nanotechnology
- Dermatology
Background:
- Skin aging results from intrinsic and extrinsic factors with shared molecular pathways.
- Conventional anti-aging ingredients face limitations like poor stability and skin penetration.
- Growing demand for effective anti-aging solutions drives cosmetic innovation.
Purpose of the Study:
- To review emerging nanotechnology-based approaches for skin anti-aging.
- To highlight the advantages of nanocarriers over conventional anti-aging agents.
- To discuss the potential of cosmeceutical nanomaterials in the anti-aging market.
Main Methods:
- Review of current literature on skin aging mechanisms.
- Analysis of various nanotechnological delivery systems (liposomes, niosomes, etc.).
- Comparison of nanocarriers with conventional phytocompounds and cosmetic ingredients.
Main Results:
- Nanotechnology offers novel solutions like liposomes, niosomes, and solid lipid nanoparticles for enhanced anti-aging efficacy.
- Nanocarriers demonstrate superior chemical stability and skin penetration compared to traditional ingredients.
- Cosmeceutical nanomaterials are rapidly advancing, promising significant impact on the anti-aging industry.
Conclusions:
- Nanotechnology presents a transformative approach to combating skin aging.
- Novel nanocarriers overcome limitations of conventional anti-aging ingredients.
- The cosmeceutical nanomaterial field is poised for substantial growth and innovation.
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