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Gap controlled self-assembly Au@Ag@Au NPs for SERS assay of thiram
Jiale Zhang1, Caijun Wu1, Ruo Yuan1
1Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University) Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, PR China.
Abstract:
Thiram (TRM), one dithiocarbamate fungicide, is hazardous due to its ever-growing threat to our production and living. In order to detecting TRM more sensitively, a subtle surface-enhanced Raman scattering (SERS) substrate was reported to achieve TRM detection based on oil-water biphasic self-assembly interface of multi-interstitial Au@Ag@Au NPs crosslinking with 4,4' -Diamino-p-Terphenyl (DATP). This Au@Ag@Au@DATP array shows a noteworthy enhanced Raman signal and stability by controlling the inter-particle spacing of Au@Ag@Au NPs, which overcomes problems of traditional randomly self-assembly methods without cross linker. The Au@Ag@Au@DATP array attained the limit of detection (LOD) of 7.56 × 10-3 ppb for TRM. In addition, this work gives a new approach for controlling gap of SERS hot spot, which have distinct potential in rapid assessment and identification of pesticides on foods.
