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Published on: June 29, 2013

Fetal ureteric reflux

J E Scott

    British Journal of Urology
    |April 1, 1987
    PubMed

    Insights

    This study highlights fetal ureteric reflux (FUR) in infants with antenatal renal dilatation. Early diagnosis and monitoring are crucial as kidney function may decline over time.

    Area of Science:

    • Pediatric Nephrology
    • Urology
    • Neonatal Medicine

    Background:

    • Antenatal renal dilatation is a common finding in fetal ultrasounds.
    • Ureteric reflux, particularly fetal ureteric reflux (FUR), can lead to significant renal complications.
    • Early identification and management are critical for preserving renal function in infants.

    Purpose of the Study:

    • To describe a cohort of infants presenting with ureteric reflux and antenatal renal dilatation.
    • To investigate the incidence of parenchymal damage and functional changes in refluxing kidneys.
    • To emphasize the importance of postnatal follow-up for infants with antenatal urinary tract abnormalities.

    Main Methods:

    • Case series describing eight infants with ureteric reflux.
    • Radioisotope studies (e.g., renal scans) to assess renal parenchymal damage and function.
    • Serial investigations to monitor changes in renal status over time.

    Main Results:

    • Seven of eight infants had antenatal renal dilatation, with a high probability of fetal ureteric reflux (FUR).
    • Radioisotope studies revealed parenchymal damage in 3/7 and reduced function in 4/10 refluxing kidneys.
    • Follow-up showed no increase in parenchymal damage, but some kidneys exhibited functional deterioration, possibly due to growth-related factors.

    Conclusions:

    • Infants with antenatal renal dilatation require thorough postnatal evaluation for ureteric reflux.
    • Monitoring renal function is essential as deterioration can occur despite initial findings.
    • Detailed postnatal examination is recommended to detect and manage potential complications of fetal ureteric reflux early.

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