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Fetal ureteric reflux.

J E Scott

    British Journal of Urology
    |April 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    This study highlights fetal ureteric reflux (FUR) in infants with antenatal renal dilatation. Early diagnosis and monitoring are crucial as kidney function may decline over time.

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    Area of Science:

    • Pediatric Nephrology
    • Urology
    • Neonatal Medicine

    Background:

    • Antenatal renal dilatation is a common finding in fetal ultrasounds.
    • Ureteric reflux, particularly fetal ureteric reflux (FUR), can lead to significant renal complications.
    • Early identification and management are critical for preserving renal function in infants.

    Purpose of the Study:

    • To describe a cohort of infants presenting with ureteric reflux and antenatal renal dilatation.
    • To investigate the incidence of parenchymal damage and functional changes in refluxing kidneys.
    • To emphasize the importance of postnatal follow-up for infants with antenatal urinary tract abnormalities.

    Main Methods:

    • Case series describing eight infants with ureteric reflux.

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  • Radioisotope studies (e.g., renal scans) to assess renal parenchymal damage and function.
  • Serial investigations to monitor changes in renal status over time.

    • Main Results:

    • Seven of eight infants had antenatal renal dilatation, with a high probability of fetal ureteric reflux (FUR).
    • Radioisotope studies revealed parenchymal damage in 3/7 and reduced function in 4/10 refluxing kidneys.
    • Follow-up showed no increase in parenchymal damage, but some kidneys exhibited functional deterioration, possibly due to growth-related factors.

    Conclusions:

    • Infants with antenatal renal dilatation require thorough postnatal evaluation for ureteric reflux.
    • Monitoring renal function is essential as deterioration can occur despite initial findings.
    • Detailed postnatal examination is recommended to detect and manage potential complications of fetal ureteric reflux early.