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Related Experiment Videos

A treatment for the acute migraine attack.

E I Adam

    The Journal of International Medical Research
    |March 1, 1987
    PubMed
    Summary

    This study found a combination analgesic/anti-emetic medication effectively reduced acute migraine attack severity. The treatment showed consistent efficacy regardless of migraine history duration.

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    The Journal of the Royal College of General Practitionersยท1978
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    Area of Science:

    • Neurology
    • Pharmacology

    Background:

    • Migraine is a common neurological disorder characterized by severe head pain.
    • Acute migraine attacks require effective and rapid symptomatic relief.

    Purpose of the Study:

    • To evaluate the efficacy of a compound analgesic/anti-emetic formulation in managing acute migraine attacks.
    • To assess treatment response in relation to patient history and migraine duration.

    Main Methods:

    • A double-blind, randomized, crossover trial was conducted.
    • Thirty-four patients from a migraine clinic participated.
    • The formulation included paracetamol (acetaminophen), codeine phosphate, buclizine hydrochloride, and dioctyl sodium sulphosuccinate.

    Main Results:

    • The compound formulation significantly reduced the severity of acute migraine attacks.
    • No specific patient factors were identified that influenced the treatment response.
    • Patients with long-standing migraine (over 10 years) responded similarly to those with recent onset.

    Conclusions:

    • The tested compound analgesic/anti-emetic formulation is an effective treatment option for acute migraine.
    • Treatment efficacy is not dependent on the duration of the patient's migraine history.

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