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Updated: Sep 23, 2025

Modeling an Enzyme Active Site using Molecular Visualization Freeware

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Published on: December 25, 2021

CFVisual: an interactive desktop platform for drawing gene structure and protein architecture.

Huilong Chen^1,2, Xiaoming Song¹, Qian Shang¹

¹School of Life Science, North China University of Science and Technology, Tangshan, 063210, Hebei, China.

BMC Bioinformatics

|May 13, 2022

Summary

Researchers can now integrate gene structure and protein architecture analysis into a single image using CFVisual. This new tool aids in gene family analysis by combining phylogenetic trees, gene structures, and protein architectures for deeper insights.

Keywords:

CFVisual Domain Gene structure Motif Promoter

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Area of Science:

Bioinformatics
Genomics
Computational Biology

Background:

Gene family analysis typically involves examining gene structural characteristics like intron-exon distribution.
Amino acid sequence analysis, including motif and domain features, is also crucial for comprehensive understanding.
A lack of integrated visualization tools hinders researchers from combining these analyses effectively.

Purpose of the Study:

To develop an integrated visualization tool for gene structure and protein architecture analysis.
To provide researchers with a unified platform for gene family studies.

Main Methods:

Development of the CFVisual package using Python.
Implementation of features for drawing phylogenetic trees, gene structures, and protein architectures.
Inclusion of interactive capabilities and arbitrary image stitching.

Main Results:

CFVisual integrates gene structure and protein architecture visualization into a single image.
The tool offers rich interactivity and supports arbitrary stitching of analysis images.
CFVisual has been successfully implemented and is available as a Python package.

Conclusions:

CFVisual serves as a valuable tool for gene family analysis.
The tool aids researchers in studying gene structure and protein architecture.
CFVisual has already seen adoption and citation by the research community.