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Annoying Psoriasis and Atopic Dermatitis: A Narrative Review
Wei-Yu Chen1,2, Shao-Chuan Chen1, Shou-Yi Hsu1
1Department of Anatomy and Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.
International Journal of Molecular Sciences
|May 14, 2022
Summary
Psoriasis and atopic dermatitis are chronic inflammatory skin diseases impacting quality of life. This review details their pathogenesis, classification, incidence, and treatment options, comparing key differences.
Area of Science:
- Dermatology
- Immunology
- Public Health
Background:
- Skin diseases like psoriasis and atopic dermatitis significantly impair quality of life, leading to social and psychological dysfunction.
- These chronic conditions affect 3-10% of the global population, with increasing prevalence.
- Immune system dysfunction and chronic inflammation are key factors in their pathogenesis, damaging skin barrier function.
Purpose of the Study:
- To provide a comprehensive overview of psoriasis and atopic dermatitis.
- To discuss the pathogenesis, clinical classification, and incidence of these diseases.
- To review and compare current treatment options, including topical, systemic, and immunosuppressive therapies.
Main Methods:
- A narrative review of existing literature was conducted.
- The review focused on pathogenesis, clinical aspects, epidemiology, and therapeutic strategies.
- Comparative analysis of psoriasis and atopic dermatitis was performed.
Main Results:
- Psoriasis and atopic dermatitis are systemic chronic inflammatory diseases with significant global impact.
- Effective management requires addressing immune dysfunction and chronic inflammation.
- A range of treatments exist, including topical, systemic, and immunosuppressive medications.
Conclusions:
- Understanding the pathogenesis and differences between psoriasis and atopic dermatitis is crucial for effective treatment.
- Further research and attention are needed to develop improved therapeutic strategies for these prevalent skin conditions.
- This review offers comprehensive information to healthcare professionals and researchers on psoriasis and atopic dermatitis.
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