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Related Experiment Video

Updated: Sep 23, 2025

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

Diagnostic Workup for Patients with Solid Renal Masses: A Cost-Effectiveness Analysis.

Jasmin Runtemund¹, Johannes Rübenthaler¹, Niklas von Münchhausen²

¹Department of Radiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.

|May 14, 2022

Summary

Contrast-enhanced ultrasound (CEUS) is a cost-effective imaging strategy for diagnosing solid renal masses. This study found CEUS to be more effective and less expensive than CT and MRI for initial assessments.

Keywords:

CEUS cost-effectiveness solid renal masses

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Area of Science:

Medical Imaging
Health Economics
Oncology

Background:

Accurate differentiation of solid renal masses is vital for patient management.
While CT and MRI are standard, contrast-enhanced ultrasound (CEUS) shows high detection sensitivity.
Economic evaluation of CEUS for renal mass diagnosis is needed.

Purpose of the Study:

To evaluate the cost-effectiveness of CEUS compared to MRI and CT for diagnosing solid renal masses.

Main Methods:

A Markov decision-making model was used to assess costs and quality-adjusted life years (QALYs).
Parameters were derived from published research.
A Monte Carlo simulation with 30,000 repetitions performed sensitivity analyses.

Main Results:

CEUS had the lowest cost (USD 5539.78) and highest efficacy (12.44 QALYs).
CT and MRI were dominated by CEUS in terms of cost and efficacy.
CEUS demonstrated cost-effectiveness across sensitivity analyses.

Conclusions:

CEUS is a cost-effective imaging strategy for the initial diagnosis of solid renal masses.
CEUS offers a superior economic and efficacy profile compared to CT and MRI.