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Epidemiology, Risk Factors and Diagnosis of Small Bowel Adenocarcinoma
Thomas Aparicio1, Atanas Pachev2, Pierre Laurent-Puig3
1Gastroenterology and Digestive Oncology, Saint Louis Hospital, Assistance Publique Hôpitaux de Paris (APHP), Université de Paris, 75010 Paris, France.
Abstract:
Adenocarcinomas of the small intestine are rare tumors but their incidence is increasing. There is a slight male predominance. The median age at diagnosis is the 6th decade. The most frequent primary location is the duodenum. There is no clearly identified environmental risk factor, but adenocarcinomas of the small intestine are associated in almost 20% of cases with predisposing diseases (Crohn's disease, Lynch syndrome, familial adenomatous polyposis, Peutz-Jeghers syndrome and celiac disease).
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