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Updated: Sep 23, 2025

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
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Myopia Control Effect Is Influenced by Baseline Relative Peripheral Refraction in Children Wearing Defocus

Hanyu Zhang1,2, Carly S Y Lam1,2, Wing-Chun Tang1

  • 1Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, China.

Journal of Clinical Medicine
|May 14, 2022
PubMed
Summary

Peripheral refraction influences myopia control in Chinese children wearing DIMS lenses. Baseline myopic RPR correlated with increased myopia progression and axial elongation in DIMS wearers, suggesting personalized approaches may optimize myopia control.

Keywords:
myopiamyopia controlmyopic defocusrelative peripheral refraction

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Area of Science:

  • Ophthalmology
  • Optometry
  • Pediatric Eye Care

Background:

  • Myopia is a growing public health concern, particularly in East Asian populations.
  • Peripheral refraction (RPR) plays a role in myopia progression, but its influence on myopia control interventions is not fully understood.
  • Defocus Incorporated Multiple Segments (DIMS) lenses are a common method for myopia control.

Purpose of the Study:

  • To investigate whether baseline relative peripheral refraction (RPR) affects the efficacy of DIMS lenses in controlling myopia progression in Chinese children.
  • To analyze the relationship between baseline RPR and changes in refractive error and axial length over a two-year period.

Main Methods:

  • A two-year randomized controlled trial involving Chinese myopic children.
  • Measurement of peripheral refraction at 10°, 20°, and 30° nasal and temporal retina at six-month intervals.
  • Statistical analysis to correlate baseline RPR with myopia progression and axial length changes in DIMS and single vision (SV) lens groups.

Main Results:

  • In the DIMS group, a more myopic baseline RPR was associated with greater myopia progression and axial elongation, particularly at nasal retinal locations (10°N, 20°N).
  • In the SV group, baseline RPR correlated with myopia progression but not axial elongation after Bonferroni correction.
  • Children with baseline hyperopic RPR showed significantly less myopia progression and axial elongation with DIMS lenses compared to those with myopic RPR.

Conclusions:

  • Baseline RPR may not significantly influence myopia progression or axial elongation in single vision lens wearers.
  • DIMS lenses demonstrated better myopia control in children with baseline hyperopic RPR compared to those with myopic RPR.
  • Individualizing myopia control strategies based on peripheral retinal profiles, including RPR, could enhance treatment efficacy.