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Published on: January 7, 2016
Global perspective on pediatric growth hormone registries: a systematic review
Parisa Eslami1, Fatemeh Sayarifard2, Reza Safdari1
1Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
This review identifies 20 pediatric growth hormone (GH) registries worldwide, detailing their characteristics and objectives. The findings offer a global perspective to guide the development of future GH treatment registry systems.
Area of Science:
- Endocrinology
- Pediatrics
- Public Health
Background:
- Pediatric registries are crucial for tracking growth hormone (GH) treatment and outcomes.
- No prior systematic review has comprehensively analyzed global pediatric GH registries.
Purpose of the Study:
- To identify and characterize worldwide registries for pediatric growth hormone treatment.
- To provide a summary of the scope, purpose, and data within these registries.
Main Methods:
- A systematic literature review was conducted up to January 30th, 2021.
- Analysis included registry type, scope, data sources, target conditions, outcomes, and variables.
Main Results:
- Twenty-two articles reported on 20 distinct pediatric GH registries.
- Commonly included conditions: GH deficiency, Turner syndrome, Prader Willi syndrome, SGA, ISS, and CRI.
- Industrial funding was prevalent; key objectives included assessing treatment safety/efficacy and epidemiological surveillance.
Conclusions:
- This systematic review offers a global overview of pediatric GH registries.
- Findings can inform the design of new national and international GH registry systems.
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