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Updated: Sep 23, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
Published on: November 1, 2015
Coping with systemic lupus erythematosus in patients' words
Alain Cornet1, Davide Mazzoni2, Angela Edwards1
1Lupus Europe, Brussels, Belgium.
Patients with Systemic Lupus Erythematosus (SLE) frequently use positive attitude, social support, healthy habits, and avoiding stress to cope. These strategies are linked to patient characteristics, informing tailored interventions for better adaptation to living with SLE.
Area of Science:
- Rheumatology
- Health Psychology
Background:
- Coping strategies for Systemic Lupus Erythematosus (SLE) are diverse and not strictly adaptive or maladaptive.
- Understanding patient-described coping mechanisms is crucial for effective management.
Purpose of the Study:
- To identify and categorize the most frequent coping strategy themes used by a large cohort of SLE patients.
- To explore associations between identified coping themes and patient characteristics.
Main Methods:
- Analysis of an open-ended survey question from the 'Living with Lupus in 2020' European survey (N=3222).
- Utilized T-LAB software for word frequency analysis and hierarchical cluster analysis to form semantic themes.
- Examined correlations between coping themes and sociodemographic, disease, and quality of life variables.
Main Results:
- Five primary coping themes emerged: positive attitude (22.58%), social support (25.46%), medical treatments (10.77%), healthy habits (20.74%), and avoiding stress (20.45%).
- Each identified coping strategy demonstrated statistically significant associations with specific patient characteristics, including age and organ involvement.
Conclusions:
- Adapting to lifelong SLE may necessitate evolving coping strategies towards more effective approaches.
- Investigating the relationship between coping strategies and patient characteristics provides a foundation for developing personalized and effective interventions for SLE patients.
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