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Related Experiment Video

Updated: Sep 23, 2025

Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
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Age is associated with increased morbidity after laparoscopic appendectomy.

Audrey Stevens1, Jennie Meier2, Archana Bhat3

  • 1University of Texas Southwestern Department of Surgery, Dallas, TX; VA North Texas Healthcare System, Dallas, TX; Surgical Center for Outcomes, Implementation, and Novel Interventions (S-COIN), Dallas, TX.

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|May 14, 2022
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Summary

Older adults undergoing laparoscopic appendectomy face increased postoperative complications. However, morbidity rates were lower for older veterans compared to non-veterans in this study.

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Area of Science:

  • General Surgery
  • Geriatric Medicine
  • Surgical Outcomes Research

Background:

  • Laparoscopic appendectomy is a common emergency procedure, yet outcomes for older adults remain understudied.
  • Appendicitis incidence is higher in younger populations, leading to a data gap in geriatric appendectomy complications.

Purpose of the Study:

  • To investigate the association between patient age and postoperative complications following laparoscopic appendectomy.
  • To determine if age has a significant and nonlinear impact on morbidity after appendectomy.

Main Methods:

  • Retrospective cohort study utilizing data from the Veterans Affairs (VA) Surgical Quality Improvement Program and National Surgical Quality Improvement Program.
  • Analysis of 14,619 veterans and 349,909 non-veterans undergoing laparoscopic appendectomy between 2000-2019.
  • Logistic regression with fractional polynomials employed to model nonlinear age-outcome relationships and assess 30-day morbidity.

Main Results:

  • A significant, nonlinear relationship between age and complication risk was observed in both veteran and non-veteran cohorts.
  • For non-veterans, predicted complication probability increased with age: 9.8% at 65, 11.9% at 75, and 14.5% at 85.
  • For veterans, predicted complication probability also rose with age: 7.5% at 65, 8.3% at 75, and 9.1% at 85.

Conclusions:

  • Older age is a significant risk factor for increased postoperative complications after laparoscopic appendectomy.
  • Notably, the Veterans Affairs (VA) healthcare system demonstrated lower morbidity rates in older adults compared to non-VA hospitals.