"Routine" chemistry testing

This study examines the use and results of a multichannel chemistry test (SMAC) in asymptomatic patients attending a family practice center. Of 288 patients, 71 (25%) presenting for complete physical examinations had apparently "routine" or baseline SMACs. Forty-three (61%) had at least one abnormal value in their chemistry profiles. Most abnormal results appeared to be of little clinical significance, but few were repeated or otherwise evaluated. Screening or baseline chemistry testing is a common feature of general health evaluations, but the efficacy of such studies is not clear.