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Related Experiment Videos

"Routine" chemistry testing.

F J Romm

    Family Medicine
    |July 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Routine multichannel chemistry tests (SMAC) in asymptomatic patients frequently show abnormal values. However, most results lack clinical significance, questioning the efficacy of this common screening practice.

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    Area of Science:

    • Family Medicine
    • Clinical Chemistry
    • Diagnostic Testing

    Background:

    • Screening laboratory tests are common in general health evaluations.
    • The clinical utility of routine chemistry profiles in asymptomatic individuals is not well-established.

    Purpose of the Study:

    • To evaluate the use and results of multichannel chemistry tests (SMAC) in asymptomatic patients.
    • To assess the clinical significance of abnormal findings in baseline chemistry profiles.

    Main Methods:

    • Retrospective analysis of 288 asymptomatic patients undergoing routine physical examinations.
    • Review of Sequential Multiple Analysis Computerized (SMAC) test results.

    Main Results:

    • 71 patients (25%) had baseline SMAC tests.

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  • 43 patients (61%) exhibited at least one abnormal chemistry value.
  • Most abnormal results were of minimal clinical importance and infrequently followed up.

    • Conclusions:

    • Routine baseline SMAC testing in asymptomatic patients yields a high rate of abnormalities.
    • The clinical significance and cost-effectiveness of routine SMAC screening require further investigation.