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Updated: Sep 23, 2025

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research
Published on: March 1, 2024
Recreational runners with Achilles tendinopathy have clinically detectable impairments: A case-control study
Igor Sancho1, Dylan Morrissey2, Richard W Willy3
1Sports and Exercise Medicine, William Harvey Research Institute. Bart's and the London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom; Physiotherapy Department, University of Deusto, San Sebastian, Spain.
Objectives:
To confirm what impairments are present in runners with Achilles tendinopathy (AT) and explore the variance of AT severity in an adequately powered study.
Design:
Case-control study.
Setting:
Two private physiotherapy clinics in Australia and Spain.
Participants:
Forty-four recreational male runners with AT and 44 healthy controls matched by age, height, and weight.
Main Outcome Measures:
Demographics, activity (IPAQ-SF), pain and function (VISA-A), pain during hopping (Hop pain VAS), hopping duration, psychological factors (TSK-11, PASS20), and physical tests regarding lower-limb maximal strength and endurance.
Results:
Body mass index (BMI), activity, VISA-A, pain, and duration of hopping, TSK-11, PASS20, standing heel raise to failure, seated heel raise and leg extension 6RM, hip extension and abduction isometric torque were significantly different between groups (P < 0.05) with varied effect sizes (V = 0.22, d range = 0.05-4.18). 46% of AT severity variance was explained by higher BMI (β = -0.41; p = 0.001), weaker leg curl 6RM (β = 0.32; p = 0.009), and higher pain during hopping (β = -0.43; p = 0.001).
Conclusion:
Runners with AT had lower activity levels, lower soleus strength, and were less tall. BMI, pain during hopping, and leg curl strength explained condition severity. This information, identified with clinically applicable tools, may guide clinical assessment, and inform intervention development.
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