Related Experiment Video
Updated: Sep 23, 2025

Sample Preparation for Probe Electrospray Ionization Mass Spectrometry
Published on: February 19, 2020
Electrospray ionization mass spectrometry with wooden tips: A review
1Institute of Mass Spectrometry and Atmospheric Environment, Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air Pollution, Jinan University, Guangzhou, 510632, China.
Abstract:
Electrospray ionization (ESI) is a powerful ionization technique in mass spectrometry (MS). There has been an increasing interest for the new development of ESI technique to extend its applications. ESI-MS with wooden tips (wooden-tip ESI-MS), an ESI technique invented in 2011, enabled not only new applications but also new insights into the ESI mechanism. In this review, the technical aspects of wooden-tip ESI-MS are described, the new features of wooden-tip ESI-MS for sampling and ionization of analytes are highlighted, and the important applications of wooden-tip ESI-MS in various fields in the past 10 years, including food safety, forensic investigation, environmental analysis, biomedical analysis and protein study, are summarized. The perspectives on the further development and applications of wooden-tip ESI-MS are also discussed.
Related Concept Videos
Electrospray Ionization (ESI) Mass Spectrometry
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview
Mass Spectrometry: Overview
Chemical Ionization (CI) Mass Spectrometry
Inductively Coupled Plasma Atomic Emission Spectroscopy: Principle
The ions and electrons produced interact with the fluctuating magnetic field created by a water-cooled...
Mass Spectrometers

