Related Experiment Video
Updated: Sep 23, 2025
Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
GC-MS profiling and antibacterial activity of Solanum khasianum leaf and root extracts
Pavani Chirumamilla1, Sunitha Bai Dharavath1, Shasthree Taduri1
1Department of Biotechnology, Kakatiya University, Warangal, Telangana 506009 India.
Background:
Solanum khasianum is an important medicinal herb of the Solanaceae family. The present study was focused to determine the bioactive compounds in S. khasianum leaf and root extract by GC-MS analysis and their antibacterial activity by agar well diffusion method.
Results:
Sixteen bioactive compounds were detected in leaf extract and thirty-two compounds in root methanolic extract by GC-MS. The major potent compounds identified in leaf and root extracts were heptadecane 9-hexyl (43.65%) and stigmasterol (23.18%). The root extract showed increased antibacterial activity than leaf extract.
Conclusion:
These extracts possessed significant antibacterial activity against the tested bacterial isolates in dose-dependent manner. This study provides the phytoconstituents, antibacterial property and scientific evidence for the traditional claim and use of S. khasianum.
