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Thyroid Metastasis From Caecal Adenocarcinoma
Sheikh Muktadir Bin Momin1, Milord Hamal2, Nicola Chaston3
1Department of Otolaryngology, East Kent Hospitals University NHS Foundation Trust, Ashford, GBR.
Cureus
|May 16, 2022
Summary
Thyroid metastasis from colorectal cancer is rare, occurring in only 0.1% of cases. This case report details a patient with advanced colon cancer who developed a symptomatic thyroid nodule, emphasizing the need for clinical vigilance.
Area of Science:
- Oncology
- Endocrinology
- Surgical Pathology
Background:
- Colorectal adenocarcinoma can metastasize to unusual sites.
- Thyroid metastasis from colorectal cancer is exceptionally rare, accounting for 0.1% of surgical series.
Observation:
- A 62-year-old woman with a history of resected colon cancer presented with a growing, symptomatic right thyroid nodule.
- Imaging showed extracapsular spread, and cytology confirmed metastatic adenocarcinoma.
Findings:
- Histopathological review confirmed the thyroid nodule was metastatic adenocarcinoma originating from a colorectal primary.
- The patient underwent a complex thyroidectomy and neck dissection.
Implications:
- This case underscores the importance of considering rare metastatic sites in patients with a history of colorectal cancer.
- Early recognition and diagnosis of thyroid metastasis are crucial for appropriate treatment planning.
- Surgical management of thyroid metastases can present unique technical challenges.

