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Prevalence and Risk Factors for Rapid Eye Movement-Related Obstructive Sleep Apnea in Children

Surisa Chamnanpet1, Prakarn Tovichien2, Archwin Tanphaichitr3

  • 1Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Frontiers in Pediatrics
|May 16, 2022
PubMed

Insights

REM-related obstructive sleep apnea (OSA) affects over half of children with OSA. Female gender and sleeping in a supine position are key risk factors for this condition in children.

Area of Science:

  • Pediatric Sleep Medicine
  • Respiratory Medicine
  • Clinical Research

Background:

  • Obstructive sleep apnea (OSA) in children presents with varying mechanisms and sleep stage distributions.
  • Understanding REM-related OSA is crucial for effective diagnosis and management.

Purpose of the Study:

  • To determine the prevalence of REM-related obstructive sleep apnea (OSA) in children.
  • To identify risk factors associated with REM-related OSA in pediatric populations.

Main Methods:

  • A retrospective, cross-sectional study involving 366 children diagnosed with OSA via polysomnography (PSG).
  • REM-related OSA defined by an obstructive apnea-hypopnea index (OAHI) in REM sleep at least twice that during NREM sleep.

Main Results:

  • The prevalence of REM-related OSA was 50.3% in the studied children.
  • Children with REM-related OSA were more likely to be female and less likely to have adenotonsillar hypertrophy.
  • Independent risk factors identified were female gender and supine sleep position, with associated findings of lower nadir SpO2 and higher ODI3%.

Conclusions:

  • REM-related OSA is highly prevalent in children, affecting over half of those diagnosed with OSA.
  • OAHI during REM sleep is an important metric for future pediatric OSA research.
  • Identifying REM-related OSA can inform targeted interventions and management strategies.
Abstract

Keywords:
OSAREM sleep disorderchildrenprevalenceriskfactor

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