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Aging01:26

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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COVID-19 and the elderly.

Klara Gadó1,2, Aranka Katalin Kovács1, Gyula Domján1

  • 11 Department of Clinical Studies, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary.

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|May 16, 2022
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Summary
This summary is machine-generated.

Older adults face higher COVID-19 risks due to comorbidities and frailty. This review covers increased susceptibility, protective measures, and clinical, including ophthalmic, symptoms in geriatric patients.

Keywords:
COVID-19ageingelderlygeriatricpneumoniavenous thromboembolism

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Area of Science:

  • Geriatric Medicine
  • Infectious Diseases
  • Public Health

Background:

  • COVID-19 poses significant global health, social, and economic challenges.
  • Mutant strains of the virus continue to emerge and spread worldwide.
  • Older adults, particularly those with comorbidities and frailty, are at increased risk for severe COVID-19 and mortality.

Purpose of the Study:

  • To review factors contributing to increased COVID-19 susceptibility in older patients.
  • To outline essential protective actions for geriatric populations.
  • To summarize the clinical presentation of COVID-19 in the elderly, including ophthalmic manifestations.

Main Methods:

  • Literature review and synthesis of existing research on COVID-19 in older adults.
  • Analysis of epidemiological data and clinical case studies.
  • Compilation of recommendations for prevention and management strategies.

Main Results:

  • Geriatric patients exhibit heightened vulnerability to SARS-CoV-2 infection and adverse outcomes.
  • Specific comorbidities and frailty syndrome significantly elevate the risk of severe disease and death.
  • Ophthalmic symptoms are noted as a potential aspect of clinical presentation in older COVID-19 patients.

Conclusions:

  • Older adults require targeted strategies to mitigate COVID-19 risks.
  • Comprehensive understanding of susceptibility factors and clinical nuances is crucial for effective geriatric care during the pandemic.
  • Proactive measures and specialized clinical attention are necessary to protect this vulnerable population.