Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Ischemic ST-segment changes after dipyridamole infusion.

G J Laarman, J F Verzijlbergen, C A Ascoop

International Journal of Cardiology

|March 1, 1987

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Androgen Deprivation therapy for Oligo-recurrent Prostate cancer in addition to radioTherapy (ADOPT): study protocol for a randomised phase III trial.

BMC cancer·2022

Same author

Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol.

BMC cancer·2022

Same author

Five-year results of the complete versus culprit vessel percutaneous coronary intervention in multivessel disease using drug-eluting stents II (CORRECT II) study: a prospective, randomised controlled trial.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2019

Same author

Acoustic shock waves, a new weapon against angina?

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2016

Same author

Impact of percutaneous coronary intervention timing on 5-year outcome in patients with non-ST-segment elevation acute coronary syndromes. The 'wait a day' approach might be safer.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2016

Same author

Cardiac tumour.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2015

Dipyridamole infusion thallium-201 myocardial imaging detects coronary artery disease. Combining imaging with ST-segment changes improves non-invasive test sensitivity for chest pain syndromes.

Area of Science:

Cardiology
Nuclear Cardiology
Diagnostic Imaging

Background:

Chest pain syndromes necessitate accurate diagnosis of coronary arterial disease.
Non-invasive tests are crucial for evaluating patients with suspected coronary artery disease.

Purpose of the Study:

To evaluate the diagnostic utility of thallium-201 myocardial imaging combined with dipyridamole infusion for detecting coronary arterial disease.
To assess the significance of ST-segment changes during dipyridamole stress testing.

Main Methods:

Thirty consecutive patients with chest pain underwent thallium-201 myocardial imaging post-dipyridamole infusion.
Coronary angiography was performed for comparison.
Visual analysis of myocardial perfusion imaging and electrocardiographic ST-segment changes were analyzed.

Related Experiment Videos

Main Results:

Eight patients (27%) exhibited ischemic ST-segment changes following dipyridamole infusion.
All patients with ST-segment changes demonstrated significant coronary arterial disease on angiography.
Thallium-201 myocardial imaging revealed perfusion defects consistent with ischemia.

Conclusions:

Dipyridamole-induced thallium-201 myocardial imaging is a valuable non-invasive tool for diagnosing coronary arterial disease.
The addition of ST-segment analysis to dipyridamole stress testing enhances the sensitivity of this diagnostic approach.
This combined method offers improved detection of significant coronary arterial disease in patients presenting with chest pain.