Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

1.3K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
1.3K
Equilibrium and Balance01:15

Equilibrium and Balance

5.1K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association Between a History of Contact Sport Participation and Higher Lifetime Mild Traumatic Brain Injury Burden Among Military Servicemembers and Veterans: A Long-term Impact of Military-relevant Brain Injury Consortium-Chronic Effects of Neurotrauma Consortium Prospective Longitudinal Study (LIMBIC-PLS).

Orthopaedic journal of sports medicine·2026
Same author

The "healthy dyad" bias in veteran-caregiver dyadic research: a methodological caution.

Innovation in aging·2026
Same author

Home- and Community-Based Service Use and Preferences Among Post-9/11 Veterans With or at High Risk of Alzheimer Disease and Related Dementia and Their Caregivers: Protocol for a Mixed Methods Observational Study.

JMIR research protocols·2026
Same author

A consensus roadmap for post-traumatic epilepsy: Clinical biomarkers, research priorities, policy barriers, and pathways to interventional trials.

Epilepsia·2026
Same author

Efficacy and outcomes of pharmacological treatments for headaches after traumatic brain injury: A systematic review.

Cephalalgia : an international journal of headache·2026
Same author

Cortical activity during preparation and execution of balance recovery behavior in people after mild traumatic brain injury: A preliminary investigation.

medRxiv : the preprint server for health sciences·2026
Same journal

Phenotype, Severity, and Therapy of Patients With LRP4 Antibody-Associated Myasthenia Gravis in the German Myasthenia Gravis Registry.

Neurology·2026
Same journal

Association of Changes in Intrinsic Capacity With Cognitive Decline and Dementia: A Prospective Cohort Study.

Neurology·2026
Same journal

Role of the Upper Motor Neuron in the Generation of Fasciculations in Early Disease Stages of Amyotrophic Lateral Sclerosis.

Neurology·2026
Same journal

Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

Neurology·2026
Same journal

Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

Neurology·2026
Same journal

Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

Neurology·2026
See all related articles

Related Experiment Video

Updated: Sep 23, 2025

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients
09:17

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients

Published on: May 17, 2020

3.4K

Sensory Phenotypes for Balance Dysfunction After Mild Traumatic Brain Injury.

Peter C Fino1, Leland E Dibble2, Elisabeth A Wilde2

  • 1From the Departments of Health & Kinesiology (P.C.F.), and Physical Therapy and Athletic Training (L.E.D.), University of Utah; George E. Wahlen VA Salt Lake City Healthcare System (E.A.W., D.F.T.); Department of Neurology (E.A.W., P.J., M.M.C., D.F.T.), University of Utah, Salt Lake City; H. Ben Taub Department of Physical Medicine and Rehabilitation (E.A.W., H.S.L.), Baylor College of Medicine, Houston, TX; Division of Epidemiology (N.F.F.), Department of Internal Medicine, and Department of Physical Medicine and Rehabilitation (C.R.H.), University of Utah, Salt Lake City; Department of Physical Therapy (S.M.v.d.V.), Virginia Commonwealth University, Richmond; Department of Physical Medicine & Rehabilitation Services (K.M.S.), James A. Haley Veterans' Hospital; Department of Physical Therapy (K.M.S.), Morsani College of Medicine, University of South Florida, Tampa, FL; Center for Neuroscience and Regenerative Medicine (CNRM) (J.K.W.), and Department of Neurology (J.K.W.), Uniformed Services University, Bethesda, MD; Department of Medicine (M.J.V.P.), University of Utah School of Medicine, Salt Lake City; Information Decision-Enhancement and Analytic Sciences Center (M.J.V.P.), VA Salt Lake City, UT; Department of Physical Medicine and Rehabilitation (W.C.W.), Virginia Commonwealth University, Richmond; and Hunter Holmes McGuire Veterans Affairs Medical Center (W.C.W.), Richmond, VA. peter.fino@utah.edu.

Neurology
|May 16, 2022
PubMed
Summary
This summary is machine-generated.

Chronic mild traumatic brain injury (mTBI) causes diverse balance issues. Specific sensory phenotypes, not just vestibular deficits, characterize mTBI-related imbalance and guide treatment.

More Related Videos

Detecting Behavioral Deficits in Rats After Traumatic Brain Injury
07:54

Detecting Behavioral Deficits in Rats After Traumatic Brain Injury

Published on: January 30, 2018

18.3K
A Human-machine-interface Integrating Low-cost Sensors with a Neuromuscular Electrical Stimulation System for Post-stroke Balance Rehabilitation
11:06

A Human-machine-interface Integrating Low-cost Sensors with a Neuromuscular Electrical Stimulation System for Post-stroke Balance Rehabilitation

Published on: April 12, 2016

10.5K

Related Experiment Videos

Last Updated: Sep 23, 2025

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients
09:17

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients

Published on: May 17, 2020

3.4K
Detecting Behavioral Deficits in Rats After Traumatic Brain Injury
07:54

Detecting Behavioral Deficits in Rats After Traumatic Brain Injury

Published on: January 30, 2018

18.3K
A Human-machine-interface Integrating Low-cost Sensors with a Neuromuscular Electrical Stimulation System for Post-stroke Balance Rehabilitation
11:06

A Human-machine-interface Integrating Low-cost Sensors with a Neuromuscular Electrical Stimulation System for Post-stroke Balance Rehabilitation

Published on: April 12, 2016

10.5K

Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Clinical Neurology

Background:

  • Current treatments for chronic mild traumatic brain injury (mTBI) utilize symptom subtypes, but these may be too broad for accurate diagnosis.
  • Balance deficits in mTBI patients are complex and may involve multiple sensory systems, not solely vestibular impairments.
  • Understanding specific sensory phenotypes is crucial for refining treatment strategies for mTBI-related chronic effects.

Purpose of the Study:

  • To investigate the existence of dominant sensory phenotypes in individuals with chronic mTBI.
  • To identify clinical characteristics, symptom clusters, functional measures, and injury mechanisms associated with sensory phenotypes for balance control in mTBI.
  • To compare sensory phenotype presentations between individuals with and without a history of mTBI.

Main Methods:

  • Secondary analysis of the Long-Term Impact of Military-Relevant Brain Injury Consortium-Chronic Effects of Neurotrauma Consortium dataset.
  • Calculation of sensory ratios from the Sensory Organization Test to categorize individuals into one of eight sensory phenotypes.
  • Comparison of demographic, clinical, injury characteristics, symptoms, cognition, and physical function across phenotypes and groups.

Main Results:

  • Abnormal visual, vestibular, and proprioception ratios were prevalent in the mTBI group, with many exhibiting multiple sensory deficits.
  • Significant differences in global outcomes, symptom severity, and physical/cognitive functioning were observed across sensory phenotypes within the mTBI group.
  • While mTBI patients generally reported worse symptoms, those in the vestibular-deficient phenotype paradoxically reported lower symptom burdens compared to non-mTBI counterparts.

Conclusions:

  • Chronic mTBI leads to varied balance deficits stemming from complex sensory integration problems.
  • Classifying mTBI-related balance dysfunction solely under a vestibular umbrella is an oversimplification.
  • Future research should focus on precise classification of balance deficits using specific sensory phenotypes for improved clinical management.