Related Experiment Video
Updated: Sep 23, 2025

Author Spotlight: Investigating Wound Healing in Mice Models of Oronasal Fistulas
Published on: September 8, 2023
Soft palate reconstruction with free jejunum flap: Impact on the velopharyngeal insufficiency
Francesco Amendola1, Davide Spadoni2, Luigi Losco3
1Department of Plastic Surgery, I.R.C.C.S. Istituto Ortopedico Galeazzi, Via Galeazzi 4, 20197, Milan, Italy.
Abstract:
If inadequately reconstructed, large resections of the soft palate inevitably cause velopharyngeal insufficiency, nasal regurgitation and reduce speech intelligibility. A series of 12 free Jejunal flaps are presented, with 28.5 months median follow up (IQR 10.5), with evidence that the flaps provided appropriate secretions and good functionality for speech and resumption of oral intake. A retrospective case series was performed, from 2004 to 2020, including patients diagnosed with palate locally advanced squamous cell carcinoma and reconstructed with free jejunum flap. Twelve patients were included, with mean age of 66 years. No flap loss, thrombosis or infection were recorded. Oral feeding was achieved in all patients, on an average after 36 days from the operation. Speech intelligibility improved by 4 points in a scale 0-10. The thin, pliable, and elastic properties of the free jejunal flap are optimally suited for a functional reconstruction of the three-dimensional palatal defects. With its serous and mucous secretion, the free jejunal flap can lead to early return to solid diet and minimize functional impairment of phonation and speech.
Related Concept Videos
Suctioning the Oropharyngeal Airway
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...
Suctioning the Nasopharyngeal Airway
Equipment Required
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...

